Working Group 2 Development of Curation Guidelines and Standards
The objective of this WG is the creation of an inventory and analysis of curation protocols, and assess how ontology improvements and text mining can be integrated in curation workflows, for the following areas:
Area a: Gene regulators – The protein level
Objective: Make recommendations for curation approaches in various subdomains of regulator proteins and their functions.
Area b: Gene regulators – The RNA level (miRNA and other non-coding RNA)
Objective: Make recommendations for curation approaches for various regulatory ncRNA species and their functions.
Area c: The nucleotide sequence recognition level
Objective: Provide guidelines, standards and protocols that will allow proper description, annotation, curation and sharing of information concerning DNA sequence profiles that represent transcription factor (TF) preferences in binding to DNA.
Area d: The genome level
Objective: Provide guidelines, standards and protocols that will allow proper description, annotation, curation, integration and sharing of information of importance concerning DNA regulatory sequence domains, nucleotide and histone modifications, protein occupancy and chromatin accessibility that impinge on gene expression regulation.
Area e: The interaction level
Objective: Make recommendations for curation standards pertaining to the interactions between gene expression regulators in complexes.