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GRKC Resources

GENE REGULATION KNOWLEDGE COMMONS RESOURCES

The Gene Regulation Knowledge Commons is defined as  “The collection of freely accessible gene regulation information resources, containing information that is well annotated with unambiguous descriptors according to quality criteria and standards that allow seamless integration and interoperability as well as automated computational access with third-party software” (Kuiper et al., 2022). Albeit still largely incomplete, an overview of available tools and resources is given below.


TOOLS

Authors:  Pau Badia-i-Mompel et al. (paper link). Type: TF-TG, phosphoproteomics

Authors: Alvarez, Mariano J., et al. (paper link) Type: TF-TG

Authors: Balwierz, Piotr J., et al. (paper link) Type: RNAseq

Authors: Dugourd, Aurelien, et al. (paper link) Type: multi-omics

Authors: Bradley G. and Barrett S.J. (paper link) Type: SIF

Authors: Liu, Anika, et al. (paper link) Type: PKN, TF-TG, DEG

Authors: Schubert, Michael, et al. (paper link) Type: PKN, DEG

Authors: Martignetti, Loredana, et al. (paper link) Type: TF-TG

Authors: Nguyen, Nga Thi Thuy, et al. (paper link) Type: RNAseq

 

Authors: Sarkans, Ugis, et al. (paper link) Type: gene expression data

Authors: Barretina, Jordi, et al. (paper link) Type: cell line data

Authors: Abugessaisa, Imad, et al. (paper link) Type: RNA annotations and CRMs

Authors: Kulakovskiy, Ivan V., et al.. (paper link) Type: transcription factor binding models

Authors: Del Toro, Noemi, et al. (paper link) Type: Molecular interaction database

Authors: Kanehisa, Minoru et al. (paper link) Type: database of genes and genomes

Authors: Shazman, Shula, et al. (paper link) Type: Drosophila melanogaster TF database

Authors: Jassal, Bijay, et al. (paper link) Type: pathway database

Authors: Fazekas, Dávid, et al. (paper link) Type: signaling pathways

Authors: Essaghir A. Demoulin J-B.  (paper link) Type: annotated TF-TG database

Author: Han, Heonjong, et al. (paper link) Type: transcriptional regulatory networks database

Author: Papatheodorou, Irene, et al. (paper link) Type: gene expression data

Authors: Lovering R.C. et al.  (paper link) Type: DNA binding TF catalogue

Authors: Barrett T, and Edgar R. (paper link) Type: gene expression data

Authors: Abramov, Boytsov et al.. (paper link) Type: human TF allele-specific binding

Authors: Baitaluk, M. et al. (paper link) Type: search engine based on the Semantic Web technologies

Authors: The Wistar Institute. (paper link) Type: gene promoters database

Authors: Lesurf, R. et al. (paper link) Type: curated regulatory annotation database

Authors:  Gallo, S.M. et al. (paper link) Type: Regulatory element database for Drosophila 

Authors: Licata, L. et al. (paper link) Type: Causal networks database

Authors: Chawla, K. et al. (paper link) Type: TF list lookup database

Authors: Teixeira, M.C. et al (paper link) Type: Saccharomyces cerevisiae TF database

Authors: Holmås, S. et al. (paper link) Type: RDF, tfact2gene graph

Authors: Garcia-Alonso, L. et al. (paper link) Type: TF-TG resource

Authors: Huang, T. et al. (paper link) Type: TF-TG resource

Authors: Bovolenta, L.A. et al. (paper link) Type: Human TF regulation interaction database

Authors: Janky, R. et al. (paper link) Type: TF-target subnetworks

Authors: Dass, G. et al. (paper link) Type: omics data lookup

Authors: Portales-Casamar, E. et al. (paper link) Type: TF and regulatory sequence database

Authors: Santos-Zavaleta, A. et al, (paper link) Type: gene regulation in Escherichia coli K-12

Authors: Tomczak, K. et al. (paper link) Type: Cancer genomics datasets and database

Authors: Wingender, E. et al. (paper link) Type: classification of eukaryotic TFs

Authors: Sarkans, U. et al. (paper link) Type: gene expression data

Authors: Vazquez M et al. (paper link) Type: TF-TG datasets

Authors: Huntley, R.P. (paper link) Type: GO annotation database

Authors: Zhang, J. et al. (paper link) Type: Cancer genomics data sets

Authors: Fornes, O. et al. (paper link) Type: eukaryote TF binding profiles

Authors: Türei, D et al. (paper link) Type: database of causal interactions

Authors: Zhang, J. et al. (paper link) Type: protein identification database

Authors: Hammal, F. et al. (paper link) Type: regulatory regions database

Authors: Schmeier, S. (paper link) Type: transcription co-factors and TF database

Authors: Wingender, E. et al. (paper link) Type: eukaryotic TF databases